Circadian rhythms are periodic changes in a variety of physiological, biochemical and even genetic processes throughout the day. Today we know that circadian rhythms are a very ancient mechanism found in all major groups of organisms, hence it is something intrinsic for all living matter. As sunlight enabled photosynthesis in plants and other photosynthetic creatures, natural selection favoured the emergence of biological mechanisms that adjusted timing of the most important processes to daylight. We would expect that humans should not depend that much on illumination. However, we depend on the temperature that in many places on the planet differs a lot between day and night. Banal dark also significantly complicated any activity back then. Finally, all living beings are connected to each other through the food chain, so the life of photosynthetic organisms directly influenced others too.
Thanks to evolution, people now have special genes regulating circadian rhythms and for their discovery and description the
2017 Nobel Prize for Physiology was awarded to Jeffrey Hall, Michael W. Young and Michael Rosbash. Researchers found that genes associated with circadian rhythms function as molecular oscillators and self-regulate through the principle of negative feedback. They synthesise proteins that themselves block such gene’s activity when the level of these proteins exceeds a certain threshold. The period of work of such an oscillator is just about 24 hours. This is our internal regulation but external stimuli also have influence on it.
What impacts our biological clocks: The key regulating signal is light interacting with the retina of our eyes, but not only. Temperature, food intake, physical activity, stress, changing time zones - all this can affect the work of our biological clocks. More importantly, gadgets can seriously disturb them too. Our retina features specific photosensitive cells called ganglion cells that are activated with a blue light, emitted from our PC or phone screens. These cells are connected to brain structures regulating release of hormones like insulin, cortisol or melatonin. Melatonin is natural relaxant produced when it’s getting dark to help us fall asleep easier. If you spend all evening exposed to artificial blue light, melatonin production slows down making it harder for you to fall asleep and restore energy resources for the next day.
Being such an ancient mechanism, Circadian rhythms cannot be surpassed or tricked easily. Coffee and cold showers or other stresses can mobilise your energy for a short period of time, but they don’t work in the long run. A number of studies have demonstrated that people fighting their inherent clock end up having a range of health issues such as insomnia, digestive disorders, obesity, cardiovascular diseases and premature death. The scientific consensus is clear:
one shall live and work according to their own body clock manifested in their chronotype.